When you’re first fitted for new dentures, it’s normal to experience minor irritation, which should fade as your mouth becomes accustomed to them. The period of pain varies. If you’ve previously worn dentures and now have a new set it may take longer. Similarly, if you had some natural teeth present that were removed at the time of the new dentures, the areas where the extractions were performed may be painful or uncomfortable for up to several weeks after the removal of the teeth. Regular visits to your denturist to adjust the dentures as you go through the normal healing process are recommended.